Levothyroxine 50 mcg tablet full#
The average full replacement dose of Levothyroxine sodium tablets is approximately 1.6 mcg per kg per day (for example: 100 mcg per day to 125 mcg per day for a 70 kg adult).Īdjust the dose by 12.5 mcg to 25 mcg increments every 4 to 6 weeks until the patient is clinically euthyroid and the serum TSH returns to normal. Start Levothyroxine sodium tablets at the full replacement dose in otherwise healthy, non-elderly individuals who have been hypothyroid for only a short time (such as a few months).
Primary Hypothyroidism in Adults and in Adolescents in Whom Growth and Puberty are Complete The peak therapeutic effect of a given dose of Levothyroxine sodium tablets may not be attained for 4 to 6 weeks. Dosing must be individualized to account for these factors and dose adjustments made based on periodic assessment of the patient's clinical response and laboratory parameters. The dose of Levothyroxine sodium tablets for hypothyroidism or pituitary TSH suppression depends on a variety of factors including: the patient's age, body weight, cardiovascular status, concomitant medical conditions (including pregnancy), concomitant medications, co-administered food and the specific nature of the condition being treated. Do not administer in foods that decrease absorption of Levothyroxine sodium tablets, such as soybean-based infant formula. Īdminister Levothyroxine sodium tablets to infants and children who cannot swallow intact tablets by crushing the tablet, suspending the freshly crushed tablet in a small amount (5 mL to 10 mL or 1 teaspoon to 2 teaspoons) of water and immediately administering the suspension by spoon or dropper. Įvaluate the need for dose adjustments when regularly administering within one hour of certain foods that may affect Levothyroxine sodium tablets absorption. Levothyroxine Dosage and Administration General Administration InformationĪdminister Levothyroxine sodium tablets as a single daily dose, on an empty stomach, one-half to one hour before breakfast.Īdminister Levothyroxine sodium tablets at least 4 hours before or after drugs known to interfere with Levothyroxine sodium tablets absorption. Levothyroxine sodium tablets are not indicated for treatment of hypothyroidism during the recovery phase of subacute thyroiditis.Levothyroxine sodium tablets are not indicated for suppression of benign thyroid nodules and nontoxic diffuse goiter in iodine-sufficient patients as there are no clinical benefits and overtreatment with Levothyroxine sodium tablets may induce hyperthyroidism.Levothyroxine sodium tablets are indicated as an adjunct to surgery and radioiodine therapy in the management of thyrotropin-dependent well-differentiated thyroid cancer.
Pituitary Thyrotropin (Thyroid-Stimulating Hormone, TSH) Suppression Levothyroxine sodium tablets are indicated as a replacement therapy in primary (thyroidal), secondary (pituitary), and tertiary (hypothalamic) congenital or acquired hypothyroidism. Larger doses may produce serious or even life threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects. In euthyroid patients, doses within the range of daily hormonal requirements are ineffective for weight reduction. Thyroid hormones, including Levothyroxine sodium tablets, either alone or with other therapeutic agents, should not be used for the treatment of obesity or for weight loss. WARNING: NOT FOR TREATMENT OF OBESITY OR FOR WEIGHT LOSS
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